Cargando…
Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial
Down syndrome (DS) is the most common genetic cause of intellectual disability. The N-methyl-D-aspartate (NMDA) receptor uncompetitive antagonist, memantine hydrochloride (memantine), has been shown to improve learning/memory and rescue one form of hippocampus synaptic plasticity dysfunction in the...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410988/ https://www.ncbi.nlm.nih.gov/pubmed/22806212 http://dx.doi.org/10.1038/tp.2012.66 |