Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains

K(2P)2.1 (TREK-1) is a polymodal two-pore domain leak potassium channel that responds to external pH, GPCR-mediated phosphorylation signals, and temperature through the action of distinct sensors within the channel. How the various intracellular and extracellular sensory elements control channel fun...

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Detalles Bibliográficos
Autores principales: Bagriantsev, Sviatoslav N, Clark, Kimberly A, Minor, Daniel L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411076/
https://www.ncbi.nlm.nih.gov/pubmed/22728824
http://dx.doi.org/10.1038/emboj.2012.171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411076/
https://www.ncbi.nlm.nih.gov/pubmed/22728824
http://dx.doi.org/10.1038/emboj.2012.171

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