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Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates
14-3-3 proteins regulate cellular responses to stimuli by docking onto pairs of phosphorylated residues on target proteins. The present study shows that the human 14-3-3-binding phosphoproteome is highly enriched in 2R-ohnologues, which are proteins in families of two to four members that were gener...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411107/ https://www.ncbi.nlm.nih.gov/pubmed/22870394 http://dx.doi.org/10.1098/rsob.120103 |