Cargando…

The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation

Insulin-stimulated glucose uptake by the glucose transporter GLUT4 plays a central role in whole-body glucose homeostasis, dysregulation of which leads to type 2 diabetes. However, the molecular components and mechanisms regulating insulin-stimulated glucose uptake remain largely unclear. Here, we d...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Hui-Ling, Zhang, Cixiong, Liu, Qi, Li, Qinxi, Lian, Guili, Wu, Di, Li, Xuebin, Zhang, Wei, Shen, Yuemao, Ye, Zhiyun, Lin, Shu-Yong, Lin, Sheng-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411167/
https://www.ncbi.nlm.nih.gov/pubmed/22473005
http://dx.doi.org/10.1038/cr.2012.52