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Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour

AIMS/HYPOTHESIS: Hypothalamic glucose-excited (GE) neurons contribute to whole-body glucose homeostasis and participate in the detection of hypoglycaemia. This system appears defective in type 1 diabetes, in which hypoglycaemia commonly occurs. Unfortunately, it is at present unclear which molecular...

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Detalles Bibliográficos
Autores principales: Beall, C., Hamilton, D. L., Gallagher, J., Logie, L., Wright, K., Soutar, M. P., Dadak, S., Ashford, F. B., Haythorne, E., Du, Q., Jovanović, A., McCrimmon, R. J., Ashford, M. L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411292/
https://www.ncbi.nlm.nih.gov/pubmed/22760787
http://dx.doi.org/10.1007/s00125-012-2617-y