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Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour
AIMS/HYPOTHESIS: Hypothalamic glucose-excited (GE) neurons contribute to whole-body glucose homeostasis and participate in the detection of hypoglycaemia. This system appears defective in type 1 diabetes, in which hypoglycaemia commonly occurs. Unfortunately, it is at present unclear which molecular...
Autores principales: | Beall, C., Hamilton, D. L., Gallagher, J., Logie, L., Wright, K., Soutar, M. P., Dadak, S., Ashford, F. B., Haythorne, E., Du, Q., Jovanović, A., McCrimmon, R. J., Ashford, M. L. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411292/ https://www.ncbi.nlm.nih.gov/pubmed/22760787 http://dx.doi.org/10.1007/s00125-012-2617-y |
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