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Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion

AIMS/HYPOTHESIS: Several glucose-sensing pathways have been implicated in glucose-triggered secretion of glucagon-like peptide-1 (GLP-1) from intestinal L cells. One involves glucose metabolism and closure of ATP-sensitive K(+) channels, and another exploits the electrogenic nature of Na(+)-coupled...

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Detalles Bibliográficos
Autores principales: Parker, H. E., Adriaenssens, A., Rogers, G., Richards, P., Koepsell, H., Reimann, F., Gribble, F. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411305/
https://www.ncbi.nlm.nih.gov/pubmed/22638549
http://dx.doi.org/10.1007/s00125-012-2585-2