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Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells

Transdifferentiation, where differentiated cells are reprogrammed into another lineage without going through an intermediate proliferative stem cell-like stage, is the next frontier of regenerative medicine. Wernig et al. first described the direct conversion of fibroblasts into functional induced n...

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Detalles Bibliográficos
Autores principales: Adler, Andrew F, Grigsby, Christopher L, Kulangara, Karina, Wang, Hong, Yasuda, Ryohei, Leong, Kam W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411320/
https://www.ncbi.nlm.nih.gov/pubmed/23344148
http://dx.doi.org/10.1038/mtna.2012.25