Increased JNK1 Signaling Pathway Is Responsible for ABCG2-Mediated Multidrug Resistance in Human Colon Cancer

Multidrug resistance remains a major obstacle to effective chemotherapy of colon cancer. ABCG2, as a half-transporter of the G subfamily of ATP-binding cassette transporter genes (ABC transporters), is known to play a crucial role in multidrug resistance. However, the molecular mechanism of controll...

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Detalles Bibliográficos
Autores principales: Zhu, Ming Ming, Tong, Jin Lu, Xu, Qi, Nie, Fang, Xu, Xi Tao, Xiao, Shu Dong, Ran, Zhi Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411563/
https://www.ncbi.nlm.nih.gov/pubmed/22870247
http://dx.doi.org/10.1371/journal.pone.0041763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411563/
https://www.ncbi.nlm.nih.gov/pubmed/22870247
http://dx.doi.org/10.1371/journal.pone.0041763

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