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Conserved Immune Recognition Hierarchy of Mycobacterial PE/PPE Proteins during Infection in Natural Hosts

The Mycobacterium tuberculosis genome contains two large gene families encoding proteins of unknown function, characterized by conserved N-terminal proline and glutamate (PE and PPE) motifs. The presence of a large number of PE/PPE proteins with repetitive domains and evidence of strain variation ha...

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Detalles Bibliográficos
Autores principales: Vordermeier, H. Martin, Hewinson, R. Glyn, Wilkinson, Robert J., Wilkinson, Katalin A., Gideon, Hannah P., Young, Douglas B., Sampson, Samantha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411574/
https://www.ncbi.nlm.nih.gov/pubmed/22870206
http://dx.doi.org/10.1371/journal.pone.0040890