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Conserved Immune Recognition Hierarchy of Mycobacterial PE/PPE Proteins during Infection in Natural Hosts
The Mycobacterium tuberculosis genome contains two large gene families encoding proteins of unknown function, characterized by conserved N-terminal proline and glutamate (PE and PPE) motifs. The presence of a large number of PE/PPE proteins with repetitive domains and evidence of strain variation ha...
Autores principales: | Vordermeier, H. Martin, Hewinson, R. Glyn, Wilkinson, Robert J., Wilkinson, Katalin A., Gideon, Hannah P., Young, Douglas B., Sampson, Samantha L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411574/ https://www.ncbi.nlm.nih.gov/pubmed/22870206 http://dx.doi.org/10.1371/journal.pone.0040890 |
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