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Association between Tetrodotoxin Resistant Channels and Lipid Rafts Regulates Sensory Neuron Excitability
Voltage-gated sodium channels (VGSCs) play a key role in the initiation and propagation of action potentials in neurons. Na(V)1.8 is a tetrodotoxin (TTX) resistant VGSC expressed in nociceptors, peripheral small-diameter neurons able to detect noxious stimuli. Na(V)1.8 underlies the vast majority of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411591/ https://www.ncbi.nlm.nih.gov/pubmed/22870192 http://dx.doi.org/10.1371/journal.pone.0040079 |