Membrane-Sensitive Conformational States of Helix 8 in the Metabotropic Glu2 Receptor, a Class C GPCR

The recent elucidation of the X-ray structure of several class A GPCRs clearly indicates that the amphipathic helix 8 (H8) is a conserved structural domain in most crystallized GPCRs. Very little is known about the presence and the possible role of an analogous H8 domain in the distantly related cla...

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Detalles Bibliográficos
Autores principales: Bruno, Agostino, Costantino, Gabriele, de Fabritiis, Gianni, Pastor, Manuel, Selent, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411606/
https://www.ncbi.nlm.nih.gov/pubmed/22870276
http://dx.doi.org/10.1371/journal.pone.0042023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411606/
https://www.ncbi.nlm.nih.gov/pubmed/22870276
http://dx.doi.org/10.1371/journal.pone.0042023

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