Cargando…

Membrane-Sensitive Conformational States of Helix 8 in the Metabotropic Glu2 Receptor, a Class C GPCR

The recent elucidation of the X-ray structure of several class A GPCRs clearly indicates that the amphipathic helix 8 (H8) is a conserved structural domain in most crystallized GPCRs. Very little is known about the presence and the possible role of an analogous H8 domain in the distantly related cla...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruno, Agostino, Costantino, Gabriele, de Fabritiis, Gianni, Pastor, Manuel, Selent, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411606/
https://www.ncbi.nlm.nih.gov/pubmed/22870276
http://dx.doi.org/10.1371/journal.pone.0042023