Functional Characterization of 8-Oxoguanine DNA Glycosylase of Trypanosoma cruzi

The oxidative lesion 8-oxoguanine (8-oxoG) is removed during base excision repair by the 8-oxoguanine DNA glycosylase 1 (Ogg1). This lesion can erroneously pair with adenine, and the excision of this damaged base by Ogg1 enables the insertion of a guanine and prevents DNA mutation. In this report, w...

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Detalles Bibliográficos
Autores principales: Furtado, Carolina, Kunrath-Lima, Marianna, Rajão, Matheus Andrade, Mendes, Isabela Cecília, de Moura, Michelle Barbi, Campos, Priscila Carneiro, Macedo, Andrea Mara, Franco, Glória Regina, Pena, Sérgio Danilo Junho, Teixeira, Santuza Maria Ribeiro, Van Houten, Bennett, Machado, Carlos Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411635/
https://www.ncbi.nlm.nih.gov/pubmed/22876325
http://dx.doi.org/10.1371/journal.pone.0042484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411635/
https://www.ncbi.nlm.nih.gov/pubmed/22876325
http://dx.doi.org/10.1371/journal.pone.0042484

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