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Identification and Characterization of ZEL-H16 as a Novel Agonist of the Histamine H(3) Receptor
The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases. In this study, a non-imidazole compound, ZEL-H16, was identified as a novel histamine H3 receptor agonist. ZEL-H16 was found to bind to human H3R wit...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411647/ https://www.ncbi.nlm.nih.gov/pubmed/22870296 http://dx.doi.org/10.1371/journal.pone.0042185 |