Modulating Uranium Binding Affinity in Engineered Calmodulin EF-Hand Peptides: Effect of Phosphorylation

To improve our understanding of uranium toxicity, the determinants of uranyl affinity in proteins must be better characterized. In this work, we analyzed the contribution of a phosphoryl group on uranium binding affinity in a protein binding site, using the site 1 EF-hand motif of calmodulin. The re...

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Detalles Bibliográficos
Autores principales: Pardoux, Romain, Sauge-Merle, Sandrine, Lemaire, David, Delangle, Pascale, Guilloreau, Luc, Adriano, Jean-Marc, Berthomieu, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411679/
https://www.ncbi.nlm.nih.gov/pubmed/22870263
http://dx.doi.org/10.1371/journal.pone.0041922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411679/
https://www.ncbi.nlm.nih.gov/pubmed/22870263
http://dx.doi.org/10.1371/journal.pone.0041922

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