Increased Cardiovascular and Renal Risk Is Associated with Low Nephron Endowment in Aged Females: An Ovine Model of Fetal Unilateral Nephrectomy

Previously we have shown that ovariectomised (OVX) female sheep have reduced renal function and elevated blood pressure from 6 months of age following fetal uninephrectomy (uni-x) at 100 days of gestation (term  = 150 days). In the current study we examined if in intact female sheep the onset of dec...

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Detalles Bibliográficos
Autores principales: Singh, Reetu R., Jefferies, Andrew J., Lankadeva, Yugeesh R., Lombardo, Paul, Schneider-Kolsky, Michal, Hilliard, Lucinda, Denton, Kate M., Moritz, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411741/
https://www.ncbi.nlm.nih.gov/pubmed/22879965
http://dx.doi.org/10.1371/journal.pone.0042400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411741/
https://www.ncbi.nlm.nih.gov/pubmed/22879965
http://dx.doi.org/10.1371/journal.pone.0042400

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