Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays

Biotin is an essential vitamin that binds streptavidin or avidin with high affinity and specificity. As biotin is a small molecule that can be linked to proteins without affecting their biological activity, biotinylation is applied widely in biochemical assays. In our laboratory, IgM enzyme immuno a...

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Detalles Bibliográficos
Autores principales: Chen, Tingting, Hedman, Lea, Mattila, Petri S., Jartti, Laura, Jartti, Tuomas, Ruuskanen, Olli, Söderlund-Venermo, Maria, Hedman, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411747/
https://www.ncbi.nlm.nih.gov/pubmed/22879954
http://dx.doi.org/10.1371/journal.pone.0042376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411747/
https://www.ncbi.nlm.nih.gov/pubmed/22879954
http://dx.doi.org/10.1371/journal.pone.0042376

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