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MyD88-Dependent Signaling Influences Fibrosis and Alternative Macrophage Activation during Staphylococcus aureus Biofilm Infection

Bacterial biofilms represent a significant therapeutic challenge based on their ability to evade host immune and antibiotic-mediated clearance. Recent studies have implicated IL-1β in biofilm containment, whereas Toll-like receptors (TLRs) had no effect. This is intriguing, since both the IL-1 recep...

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Detalles Bibliográficos
Autores principales: Hanke, Mark L., Angle, Amanda, Kielian, Tammy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411753/
https://www.ncbi.nlm.nih.gov/pubmed/22879997
http://dx.doi.org/10.1371/journal.pone.0042476