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Association of Caucasian-Identified Variants with Colorectal Cancer Risk in Singapore Chinese

BACKGROUND: Genome-wide association studies (GWAS) in Caucasians have identified fourteen index single nucleotide polymorphisms (iSNPs) that influence colorectal cancer (CRC) risk. METHODS: We investigated the role of eleven iSNPs or surrogate SNPs (sSNPs), in high linkage disequilibrium (LD, r(2)≥0...

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Detalles Bibliográficos
Autores principales: Thean, Lai Fun, Li, Hui Hua, Teo, Yik Ying, Koh, Woon-Puay, Yuan, Jian-Min, Teoh, Mei Lin, Koh, Poh Koon, Tang, Choong Leong, Cheah, Peh Yean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411754/
https://www.ncbi.nlm.nih.gov/pubmed/22879968
http://dx.doi.org/10.1371/journal.pone.0042407