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Platelet-Derived Growth Factor Over-Expression in Retinal Progenitors Results in Abnormal Retinal Vessel Formation

Platelet-derived growth factor (PDGF) plays an important role in development of the central nervous system, including the retina. Excessive PDGF signaling is associated with proliferative retinal disorders. We reported previously that transgenic mice in which PDGF-B was over-expressed under control...

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Detalles Bibliográficos
Autores principales: Edqvist, Per-Henrik D., Niklasson, Mia, Vidal-Sanz, Manuel, Hallböök, Finn, Forsberg-Nilsson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411765/
https://www.ncbi.nlm.nih.gov/pubmed/22880002
http://dx.doi.org/10.1371/journal.pone.0042488