Fractionated Therapy of HER2-Expressing Breast and Ovarian Cancer Xenografts in Mice with Targeted Alpha Emitting (227)Th-DOTA-p-benzyl-trastuzumab

BACKGROUND: The aim of this study was to investigate therapeutic efficacy and normal tissue toxicity of single dosage and fractionated targeted alpha therapy (TAT) in mice with HER2-expressing breast and ovarian cancer xenografts using the low dose rate radioimmunoconjugate (227)Th-DOTA-p-benzyl-tra...

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Detalles Bibliográficos
Autores principales: Heyerdahl, Helen, Abbas, Nasir, Brevik, Ellen Mengshoel, Mollatt, Camilla, Dahle, Jostein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411767/
https://www.ncbi.nlm.nih.gov/pubmed/22879947
http://dx.doi.org/10.1371/journal.pone.0042345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411767/
https://www.ncbi.nlm.nih.gov/pubmed/22879947
http://dx.doi.org/10.1371/journal.pone.0042345

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