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Achieving Maximal Speed of Solution Exchange for Patch Clamp Experiments

BACKGROUND: Resolving the kinetics of agonist binding events separately from the subsequent channel gating processes requires the ability of applying and removing the agonist before channel gating occurs. No reported system has yet achieved pulses shorter than 100 µs, necessary to study nicotinic AC...

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Detalles Bibliográficos
Autores principales: Auzmendi, Jerónimo, Fernández Do Porto, Darío, Pallavicini, Carla, Moffatt, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411769/
https://www.ncbi.nlm.nih.gov/pubmed/22879927
http://dx.doi.org/10.1371/journal.pone.0042275