Inhibition of TDP-43 Accumulation by Bis(thiosemicarbazonato)-Copper Complexes

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, motor neuron disease with no effective long-term treatment options. Recently, TDP-43 has been identified as a key protein in the pathogenesis of some cases of ALS. Although the role of TDP-43 in motor neuron degeneration is not yet known,...

Descripción completa

Detalles Bibliográficos
Autores principales: Parker, Sarah J., Meyerowitz, Jodi, James, Janine L., Liddell, Jeffrey R., Nonaka, Takashi, Hasegawa, Masato, Kanninen, Katja M., Lim, SinChun, Paterson, Brett M., Donnelly, Paul S., Crouch, Peter J., White, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411774/
https://www.ncbi.nlm.nih.gov/pubmed/22879928
http://dx.doi.org/10.1371/journal.pone.0042277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411774/
https://www.ncbi.nlm.nih.gov/pubmed/22879928
http://dx.doi.org/10.1371/journal.pone.0042277

Ejemplares similares