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Storage-Induced Changes in Erythrocyte Membrane Proteins Promote Recognition by Autoantibodies

Physiological erythrocyte removal is associated with a selective increase in expression of neoantigens on erythrocytes and their vesicles, and subsequent autologous antibody binding and phagocytosis. Chronic erythrocyte transfusion often leads to immunization and the formation of alloantibodies and...

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Detalles Bibliográficos
Autores principales: Dinkla, Sip, Novotný, Věra M. J., Joosten, Irma, Bosman, Giel J. C. G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411782/
https://www.ncbi.nlm.nih.gov/pubmed/22879923
http://dx.doi.org/10.1371/journal.pone.0042250