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Impact of Sex Steroid Ablation on Viral, Tumour and Vaccine Responses in Aged Mice
Recent evidence suggests that the decline in resistance to viral infections with age occurs predominantly as a result of a gradual loss of naïve antigen-specific T cells. As such, restoration of the naïve T cell repertoire to levels seen in young healthy adults may improve defence against infection...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411797/ https://www.ncbi.nlm.nih.gov/pubmed/22880080 http://dx.doi.org/10.1371/journal.pone.0042677 |