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Impact of Sex Steroid Ablation on Viral, Tumour and Vaccine Responses in Aged Mice

Recent evidence suggests that the decline in resistance to viral infections with age occurs predominantly as a result of a gradual loss of naïve antigen-specific T cells. As such, restoration of the naïve T cell repertoire to levels seen in young healthy adults may improve defence against infection...

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Detalles Bibliográficos
Autores principales:	Heng, Tracy S. P., Reiseger, Jessica J., Fletcher, Anne L., Leggatt, Graham R., White, Olivia J., Vlahos, Katerina, Frazer, Ian H., Turner, Stephen J., Boyd, Richard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411797/ https://www.ncbi.nlm.nih.gov/pubmed/22880080 http://dx.doi.org/10.1371/journal.pone.0042677

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