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Intranasal Immunization with Nontypeable Haemophilus influenzae Outer Membrane Vesicles Induces Cross-Protective Immunity in Mice

Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and a pathogen of the respiratory tract. Especially nontypeable H. influenzae (NTHi) is a major threat to public health and is responsible for several infectious diseases in humans, such as pneumonia, si...

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Detalles Bibliográficos
Autores principales: Roier, Sandro, Leitner, Deborah R., Iwashkiw, Jeremy, Schild-Prüfert, Kristina, Feldman, Mario F., Krohne, Georg, Reidl, Joachim, Schild, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411803/
https://www.ncbi.nlm.nih.gov/pubmed/22880074
http://dx.doi.org/10.1371/journal.pone.0042664