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Mucosal Healing and Fibrosis after Acute or Chronic Inflammation in Wild Type FVB-N Mice and C57BL6 Procollagen α1(I)-Promoter-GFP Reporter Mice

BACKGROUND: Injury and intestinal inflammation trigger wound healing responses that can restore mucosal architecture but if chronic, can promote intestinal fibrosis. Intestinal fibrosis is a major complication of Crohn’s disease. The cellular and molecular basis of mucosal healing and intestinal fib...

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Detalles Bibliográficos
Autores principales: Ding, Shengli, Walton, Kristen L. W., Blue, Randall Eric, MacNaughton, Kirk, Magness, Scott T., Lund, Pauline Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411826/
https://www.ncbi.nlm.nih.gov/pubmed/22880035
http://dx.doi.org/10.1371/journal.pone.0042568