Human B-cell ontogeny in humanized NOD/SCID γc(null) mice generates a diverse yet auto/poly- and HIV-1 reactive antibody repertoire

Characterization of the human antibody (Ab) repertoire in mouse models of the human immune system is essential to establish their relevance in translational studies. Single human B-cells were sorted from bone marrow and periphery of humanized NOD/SCID γc(null) mice at 8–10 months post-engraftment wi...

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Detalles Bibliográficos
Autores principales: Chang, Hong, Biswas, Subhabrata, Tallarico, Aimee St. Clair, Sarkis, Phuong Thi Nguyen, Geng, Shusheng, Panditrao, Madhura M., Zhu, Quan, Marasco, Wayne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411862/
https://www.ncbi.nlm.nih.gov/pubmed/22592523
http://dx.doi.org/10.1038/gene.2012.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411862/
https://www.ncbi.nlm.nih.gov/pubmed/22592523
http://dx.doi.org/10.1038/gene.2012.16

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