Lyl1 regulates lymphoid specification and maintenance of early T lineage progenitors

Thymopoiesis depends on recruitment and expansion of bone marrow-derived progenitors, tight regulation of which is required to maintain T-lineage homeostasis. Lyl1, a transcription factor regulating hematopoietic progenitors, is expressed in thymocyte progenitors until T cell commitment. Here we dem...

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Detalles Bibliográficos
Autores principales: Zohren, Fabian, Souroullas, George P., Luo, Min, Gerdemann, Ulrike, Imperato, Maria R., Wilson, Nicola K., Gottgens, Berthold, Lukov, Georgi L., Goodell, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411897/
https://www.ncbi.nlm.nih.gov/pubmed/22772404
http://dx.doi.org/10.1038/ni.2365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411897/
https://www.ncbi.nlm.nih.gov/pubmed/22772404
http://dx.doi.org/10.1038/ni.2365

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