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Lyl1 regulates lymphoid specification and maintenance of early T lineage progenitors
Thymopoiesis depends on recruitment and expansion of bone marrow-derived progenitors, tight regulation of which is required to maintain T-lineage homeostasis. Lyl1, a transcription factor regulating hematopoietic progenitors, is expressed in thymocyte progenitors until T cell commitment. Here we dem...
Autores principales: | Zohren, Fabian, Souroullas, George P., Luo, Min, Gerdemann, Ulrike, Imperato, Maria R., Wilson, Nicola K., Gottgens, Berthold, Lukov, Georgi L., Goodell, Margaret A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411897/ https://www.ncbi.nlm.nih.gov/pubmed/22772404 http://dx.doi.org/10.1038/ni.2365 |
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