FGFR2 Mutation Confers a Less Drastic Gain of Function in Mesenchymal Stem Cells Than in Fibroblasts

Gain-of-function mutations in FGFR2 cause Apert syndrome (AS), a disease characterized by craniosynostosis and limb bone defects both due to abnormalities in bone differentiation and remodeling. Although the periosteum is an important cell source for bone remodeling, its role in craniosynostosis rem...

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Detalles Bibliográficos
Autores principales: Yeh, Erika, Atique, Rodrigo, Ishiy, Felipe A. A., Fanganiello, Roberto Dalto, Alonso, Nivaldo, Matushita, Hamilton, da Rocha, Katia Maria, Passos-Bueno, Maria Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press Inc 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412083/
https://www.ncbi.nlm.nih.gov/pubmed/22048896
http://dx.doi.org/10.1007/s12015-011-9327-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412083/
https://www.ncbi.nlm.nih.gov/pubmed/22048896
http://dx.doi.org/10.1007/s12015-011-9327-6

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