HRT, Herbal Formula, Induces G(2)/M Cell Cycle Arrest and Apoptosis via Suppressing Akt Signaling Pathway in Human Colon Cancer Cells

We have demonstrated the anticancer effect of HRT in HCT116, human colon carcinoma cells. HRT inhibited cancer cell growth by causing cell cycle arrest at G(2)/M and inducing apoptosis as evidenced by DNA fragmentation assay. We found that HRT induces the activation of caspase-3, -8, and -9, whereas...

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Detalles Bibliográficos
Autores principales: Yim, Nam-Hui, Cho, Won-Kyung, Lee, Ju Hye, Jung, Young Pil, Yang, Hye Jin, Ma, Jin Yeul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412102/
https://www.ncbi.nlm.nih.gov/pubmed/22899960
http://dx.doi.org/10.1155/2012/871893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412102/
https://www.ncbi.nlm.nih.gov/pubmed/22899960
http://dx.doi.org/10.1155/2012/871893

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