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The Alzheimer's Amyloid-Degrading Peptidase, Neprilysin: Can We Control It?

The amyloid cascade hypothesis of Alzheimer's disease (AD) postulates that accumulation in the brain of amyloid β-peptide (Aβ) is the primary trigger for neuronal loss specific to this pathology. In healthy brain, Aβ levels are regulated by a dynamic equilibrium between Aβ release from the amyl...

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Detalles Bibliográficos
Autores principales: Nalivaeva, N. N., Belyaev, N. D., Zhuravin, I. A., Turner, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412116/
https://www.ncbi.nlm.nih.gov/pubmed/22900228
http://dx.doi.org/10.1155/2012/383796