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The Alzheimer's Amyloid-Degrading Peptidase, Neprilysin: Can We Control It?
The amyloid cascade hypothesis of Alzheimer's disease (AD) postulates that accumulation in the brain of amyloid β-peptide (Aβ) is the primary trigger for neuronal loss specific to this pathology. In healthy brain, Aβ levels are regulated by a dynamic equilibrium between Aβ release from the amyl...
Autores principales: | Nalivaeva, N. N., Belyaev, N. D., Zhuravin, I. A., Turner, A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412116/ https://www.ncbi.nlm.nih.gov/pubmed/22900228 http://dx.doi.org/10.1155/2012/383796 |
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