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The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF

The MUC1 cytoplasmic tail (MUC1.CT) conducts signals from spatial and extracellular cues (growth factor and cytokine stimulation) to evoke a reprogramming of the cellular transcriptional profile. Specific phosphorylated forms of the MUC1.CT achieve this function by differentially associating with tr...

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Detalles Bibliográficos
Autores principales: Behrens, Michelle E., Grandgenett, Paul M., Bailey, Jennifer M., Singh, Pankaj K., Yi, Chun-Hui, Yu, Fang, Hollingsworth, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412169/
https://www.ncbi.nlm.nih.gov/pubmed/20697347
http://dx.doi.org/10.1038/onc.2010.327