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The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF
The MUC1 cytoplasmic tail (MUC1.CT) conducts signals from spatial and extracellular cues (growth factor and cytokine stimulation) to evoke a reprogramming of the cellular transcriptional profile. Specific phosphorylated forms of the MUC1.CT achieve this function by differentially associating with tr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412169/ https://www.ncbi.nlm.nih.gov/pubmed/20697347 http://dx.doi.org/10.1038/onc.2010.327 |