L1 Hybridization Enrichment: A Method for Directly Accessing De Novo L1 Insertions in the Human Germline

Long interspersed nuclear element 1 (L1) retrotransposons are the only autonomously mobile human transposable elements. L1 retrotransposition has shaped our genome via insertional mutagenesis, sequence transduction, pseudogene formation, and ectopic recombination. However, L1 germline retrotransposi...

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Detalles Bibliográficos
Autores principales: Freeman, Peter, Macfarlane, Catriona, Collier, Pamela, Jeffreys, Alec J, Badge, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412225/
https://www.ncbi.nlm.nih.gov/pubmed/21560187
http://dx.doi.org/10.1002/humu.21533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412225/
https://www.ncbi.nlm.nih.gov/pubmed/21560187
http://dx.doi.org/10.1002/humu.21533

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