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Lack of Mutagenicity Potential of Periploca sepium Bge. in Bacterial Reverse Mutation (Ames) Test, Chromosomal Aberration and Micronucleus Test in Mice

OBJECTIVES: The root barks of Periploca sepium Bge. (P. sepium) has been used in traditional Chinese medicine for healing wounds and treating rheumatoid arthritis. However, toxicity in high-doses was often diagnosed by the presence of many glycosides. The potential mutagenicity of P. sepium was inve...

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Detalles Bibliográficos
Autores principales: Zhang, Mei-Shu, Bang, In-Seok, Park, Cheol Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Environmental Health and Toxicology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412258/
https://www.ncbi.nlm.nih.gov/pubmed/22888473
http://dx.doi.org/10.5620/eht.2012.27.e2012014