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Th1/Th2 Differentiation and B Cell Function by the Atypical PKCs and Their Regulators

The members of the atypical Protein Kinase Cs (aPKC) kinase subfamily, PKCζ and PKCλ/ɩ, as well as their adapters, p62 and Par-6, form part of the PB1-domain-containing group of signaling regulators. Both adapters serve to locate through heterotypic interactions the aPKCs into the NF-κB and cell pol...

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Detalles Bibliográficos
Autores principales: Martin, Pilar, Moscat, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412266/
https://www.ncbi.nlm.nih.gov/pubmed/22888333
http://dx.doi.org/10.3389/fimmu.2012.00241