The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei

The sugar nucleotide GDP-mannose is essential for Trypanosoma brucei. Phosphomannose isomerase occupies a key position on the de novo pathway to GDP-mannose from glucose, just before intersection with the salvage pathway from free mannose. We identified the parasite phosphomannose isomerase gene, co...

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Detalles Bibliográficos
Autores principales: Kuettel, Sabine, Wadum, Majken C T, Güther, Maria Lucia S, Mariño, Karina, Riemer, Carolin, Ferguson, Michael A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412276/
https://www.ncbi.nlm.nih.gov/pubmed/22375793
http://dx.doi.org/10.1111/j.1365-2958.2012.08026.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412276/
https://www.ncbi.nlm.nih.gov/pubmed/22375793
http://dx.doi.org/10.1111/j.1365-2958.2012.08026.x

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