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A new mechanism of stem cell differentiation through slow binding/unbinding of regulators to genes
Understanding differentiation, a biological process from a multipotent stem or progenitor state to a mature cell is critically important. We developed a theoretical framework to quantify the underlying potential landscape and pathways for cell development and differentiation. We proposed a new mecha...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412324/ https://www.ncbi.nlm.nih.gov/pubmed/22870379 http://dx.doi.org/10.1038/srep00550 |