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A new mechanism of stem cell differentiation through slow binding/unbinding of regulators to genes

Understanding differentiation, a biological process from a multipotent stem or progenitor state to a mature cell is critically important. We developed a theoretical framework to quantify the underlying potential landscape and pathways for cell development and differentiation. We proposed a new mecha...

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Detalles Bibliográficos
Autores principales: Feng, Haidong, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412324/
https://www.ncbi.nlm.nih.gov/pubmed/22870379
http://dx.doi.org/10.1038/srep00550