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Calcium signaling is gated by a mechanical threshold in three-dimensional environments

Cells interpret their mechanical environment using diverse signaling pathways that affect complex phenotypes. These pathways often interact with ubiquitous 2(nd)-messengers such as calcium. Understanding mechanically-induced calcium signaling is especially important in fibroblasts, cells that exist...

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Detalles Bibliográficos
Autores principales: Ruder, Warren C., Pratt, Erica D., Brandy, Nailah Z. D., LaVan, David A., LeDuc, Philip R., Antaki, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412325/
https://www.ncbi.nlm.nih.gov/pubmed/22870383
http://dx.doi.org/10.1038/srep00554