Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation

The mitochondrial protein AFG3L2 forms homo-oligomeric and hetero-oligomeric complexes with paraplegin in the inner mitochondrial membrane, named m-AAA proteases. These complexes are in charge of quality control of misfolded proteins and participate in the regulation of OPA1 proteolytic cleavage, re...

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Detalles Bibliográficos
Autores principales: Maltecca, Francesca, De Stefani, Diego, Cassina, Laura, Consolato, Francesco, Wasilewski, Michal, Scorrano, Luca, Rizzuto, Rosario, Casari, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412383/
https://www.ncbi.nlm.nih.gov/pubmed/22678058
http://dx.doi.org/10.1093/hmg/dds214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412383/
https://www.ncbi.nlm.nih.gov/pubmed/22678058
http://dx.doi.org/10.1093/hmg/dds214

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