E2F transcription factor-1 deficiency reduces pathophysiology in the mouse model of Duchenne muscular dystrophy through increased muscle oxidative metabolism

E2F1 deletion leads to increased mitochondrial number and function, increased body temperature in response to cold and increased resistance to fatigue with exercise. Since E2f1−/− mice show increased muscle performance, we examined the effect of E2f1 genetic inactivation in the mdx background, a mou...

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Detalles Bibliográficos
Autores principales: Blanchet, Emilie, Annicotte, Jean-Sébastien, Pradelli, Ludivine A., Hugon, Gérald, Matecki, Stéfan, Mornet, Dominique, Rivier, François, Fajas, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412384/
https://www.ncbi.nlm.nih.gov/pubmed/22678059
http://dx.doi.org/10.1093/hmg/dds219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412384/
https://www.ncbi.nlm.nih.gov/pubmed/22678059
http://dx.doi.org/10.1093/hmg/dds219

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