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E2F transcription factor-1 deficiency reduces pathophysiology in the mouse model of Duchenne muscular dystrophy through increased muscle oxidative metabolism
E2F1 deletion leads to increased mitochondrial number and function, increased body temperature in response to cold and increased resistance to fatigue with exercise. Since E2f1−/− mice show increased muscle performance, we examined the effect of E2f1 genetic inactivation in the mdx background, a mou...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412384/ https://www.ncbi.nlm.nih.gov/pubmed/22678059 http://dx.doi.org/10.1093/hmg/dds219 |