Mixed Vector Immunization With Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity

Substantial protection can be provided against the pre-erythrocytic stages of malaria by vaccination first with an adenoviral and then with an modified vaccinia virus Ankara (MVA) poxviral vector encoding the same ME.TRAP transgene. We investigated whether the two vaccine components adenovirus (Ad)...

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Detalles Bibliográficos
Autores principales: Reyes-Sandoval, Arturo, Rollier, Christine S, Milicic, Anita, Bauza, Karolis, Cottingham, Matthew G, Tang, Choon-Kit, Dicks, Matthew D, Wang, Dong, Longley, Rhea J, Wyllie, David H, Hill, Adrian VS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412496/
https://www.ncbi.nlm.nih.gov/pubmed/22354374
http://dx.doi.org/10.1038/mt.2012.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412496/
https://www.ncbi.nlm.nih.gov/pubmed/22354374
http://dx.doi.org/10.1038/mt.2012.25

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