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Functional Analysis of Two PLA2G2A Variants Associated with Secretory Phospholipase A2-IIA Levels

BACKGROUND: Secretory phospholipase A2 group IIA (sPLA2-IIA) has been identified as a biomarker of atherosclerosis in observational and animal studies. The protein is encoded by the PLA2G2A gene and the aim of this study was to test the functionality of two PLA2G2A non-coding SNPs, rs11573156 C>G...

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Detalles Bibliográficos
Autores principales: Exeter, Holly J., Folkersen, Lasse, Palmen, Jutta, Franco-Cereceda, Anders, Cooper, Jackie A., Kalea, Anastasia Z., Hooft, Ferdinand van’t, Eriksson, Per, Humphries, Steve E., Talmud, Philippa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412631/
https://www.ncbi.nlm.nih.gov/pubmed/22879865
http://dx.doi.org/10.1371/journal.pone.0041139